Association of the CYP3A5 A6986G (CYP3A5*3) polymorphism with saquinavir pharmacokinetics
نویسندگان
چکیده
منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولAssociation of CYP2C8, CYP3A4, CYP3A5, and ABCB1 polymorphisms with the pharmacokinetics of paclitaxel.
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Objectives: Sirolimus (SRL) is a widely used immunosuppressive agent in preventing allograft rejection after solid organ transplantation. In this study we established a population pharmacokinetic (PPK) model for SRL in Chinese renal transplant patients, and elucidated the influence of CYP3A5*3 genotypes on SRL PPK parameters and SRL dosing regimen in Chinese renal transplant recipients. Methods...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2004
ISSN: 0306-5251,1365-2125
DOI: 10.1111/j.1365-2125.2004.02159.x